Rheumatoid arthritis and mycoplasma infection




Arthritis is a general term for diseases associated with inflammation of the joints. Symptoms include local and systemic symptoms. Local symptoms include redness, swelling, tenderness, stiffness, and limited range of motion, and systemic symptoms include fever, general malaise, and weight loss.


Arthritis has various pathological conditions such as bacterial arthritis, tuberculous arthritis, rheumatoid arthritis, gout, pseudogout, psoriatic arthritis, and degenerative arthritis. Diagnosis and treatment differ depending on the condition.


Early stages of chronic arthritis may appear to be acute arthritis, and such disorders include connective tissue disorders such as rheumatoid arthritis, SLE, and vasculitis.


Polymyalgia rheumatica, which is characterized by neck, shoulder, and lumbar symptoms in the elderly, is known to be associated with temporal arteritis.


Mycoplasma infections are becoming known to be the cause of rheumatoid arthritis and even rheumatism. In particular, he is well known for mycoplasma fermentance.


Related Links

  • Kawahito Y, Ichinose S, Sano H, Tsubouchi Y, Kohno M, Yoshikawa T, Tokunaga D, Hojo T, Harasawa R, Nakano T, Matsuda K. Mycoplasma fermentans glycolipid-antigen as a pathogen of rheumatoid arthritis. Biochem Biophys Res Commun. 369:561-566. (2008)

  • Gil C, Rivera A, Banuelos D, Salinas S, Garcia-Latorre E, Cedillo L. Presence of Mycoplasma fermentans in the bloodstream of Mexican patients with rheumatoid arthritis and IgM and IgG antibodies against whole microorganism. BMC Musculoskelet Disord. 10:97 (2009).

  • Horowitz S, Evinson B, Borer A, Horowitz J. Mycoplasma fermentans in rheumatoid arthritis and other inflammatory arthritides. J Rheumatol. 27:2747-2753. (2000)

  • Schaeverbeke T, Gilroy CB, Bebear C, Dehais J, Taylor-Robinson D. Mycoplasma fermentans, but not M penetrans, detected by PCR assays in synovium from patients with rheumatoid arthritis and other rheumatic disorders. J Clin Pathol. 49:824-828. (1996)